IMPACT OF NONRANDOM SELECTION MECHANISMS ON THE CAUSAL EFFECT ESTIMATION FOR TWO-SAMPLE MENDELIAN RANDOMIZATION METHODS.

Impact of nonrandom selection mechanisms on the causal effect estimation for two-sample Mendelian randomization methods.

Nonrandom selection in one-sample Mendelian Randomization (MR) results in biased estimates and inflated type I error rates only when the selection effects are sufficiently large.In two-sample MR, the different selection mechanisms in two samples may more seriously affect the causal effect estimation.Firstly, we propose sufficient conditions for cau

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Genetic variability and phenotypic diversity in populations of the Eurasian perch, Perca fluviatilis (Actinopterygii, Percidae)

The Eurasian perch Perca fluviatilis (Linnaeus, 1758) is a common species of fish in northern ecosystems.The species demonstrates high phenotypic diversity when it inhabits various types of water bodies.Here, we investigate whether there is a relationship between the genetic variability and phenotypic diversity in natural perch populations.Perca fl

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